Formulari Ubat KKM (FUKKM)

# Generic Name MDC Category Indications Pres. Restrictions Dosage
1 Fentanyl 12mcg/h Transdermal Patch N02AB03-136-M70-05-XXX A* As a second line drug in the management of opioid responsive, moderate to severe chronic cancer pain. None ADULT and CHILD over 2 years previously treated with a strong opioid analgesic, initial dose based on previous 24-hour opioid requirement (consult product literature). If necessary dose should be adjusted at 72-hour intervals in steps of 12-25 mcg/hr
2 Fentanyl 25 mcg/h Transdermal Patch N02AB03-136-M70-01-XXX A*, A/KK Category Prescriber A*:
i) As a second line drug in the management of opioid responsive, moderate chronic cancer pain

Category Prescriber A/KK:
ii) As a second line drug in the management of opioid responsive, severe chronic cancer pain		 Indikasi ii)
Category Prescriber A/KK: To be prescribed by Family Medicine Specialists trained in pain management		 Patients who have not previously received a strong opioid analgesic, initial dose , one 25 mcg/hour patch to be replaced after 72 hours. Patients who have received a strong opioid analgesic, initial dose based on previous 24 hours opioid requirement (oral morphine sulphate 90 mg over 24 hours = one 25 mcg/hour patch). Not recommended in children.
3 Fentanyl 50mcg/h Transdermal Patch N02AB03-136-M70-02-XXX A* As a second line drug in the management of opioid responsive, moderate to severe chronic cancer pain None Patients who have not previously received a strong opioid analgesic, initial dose , one 25 mcg/hour patch to be replaced after 72 hours. Patients who have received a strong opioid analgesic, initial dose based on previous 24 hours opioid requirement (oral morphine sulphate 90 mg over 24 hours = one 25 mcg/hour patch). Not recommended in children.
4 Fentanyl Citrate 50mcg/ml Injection N01AH01-136-P30-01-XXX A Short duration analgesia during pre-medication induction and maintenance of anaesthesia, and in the immediate post-operative period. Dose should be individualized according to age, body weight, physical status, underlying pathological conditions and type of surgery and anaesthesia. ADULT: Premedication: IM 50 - 100 mcg, 30 - 60 mins prior to surgery. Adjunct to general anaesthesia: Induction IV 50 - 100mcg, repeat 2 - 3 mins intervals until desired effect is achieved. IV/IM 25 - 50mcg in elderly and poor risk patients. Maintenance: IV/IM 25 - 50mcg. Adjunct to regional anaesthesia: IM/slow IV 50 - 100mcg when additinal analgesia is required. Post-operatively (recovery room): IM 50 - 100mcg for pain control, tachypnoea and emergency delirium. May be repeated in 1- 2 hours as needed. CHILD (2 - 12 years): Induction & maintenance: 2 - 3 mcg/kg.