Formulari Ubat KKM (FUKKM)

# Generic Name MDC Category Indications Pres. Restrictions Dosage
1681 Zoledronic Acid 4 mg Injection M05BA08000P3001XX A* i) Treatment of hypercalcaemia of malignancy
ii) Prevention of skeletal related events (SREs) in patients with multiple myeloma involving multiple bone lesions
iii) Prevention of skeletal related events (SREs) for metastatic cancers of solid tumours		 i) 4mg single dose
ii) 4mg every 3-4 weeks
iii) 4mg reconstituted and should be given as a 15- minute IV infusion every 12 weeks (as advised in MaHTAS 2018 Report)
1682 Zolpidem Tartrate 10 mg Tablet N05CF02123T1001XX A For treatment of insomnia ADULT: 10mg daily at bedtime
ELDERLY OR DEBILITATED SUBJECTS: 5mg daily at bed time
Max. dose: 10mg daily
1683 Zonisamide 100mg tablet N03AX15-000-T10-01-XXX A* As adjunctive therapy in the treatment of partial seizures in adults with epilepsy. As adjunctive therapy in the treatment of partial seizures in adults with epilepsy when 1st line and 2nd line therapy failed. For adults, usually 100 to 200mg of zonisomide is to be administered orally 1 to 3 times a day initially. The dose is gradually increased at every one to two weeks up to 200-400mg daily, in 1 to 3 divided dose. The maximum daily dose should not exceed 600mg per day.
1684 Zuclopenthixol 20 mg/ml Drops N05AF05000D5001XX A* i) Acute schizophrenia and other acute psychoses, including agitation
ii) Chronic schizophrenia and other chronic psychoses
iii) Mania		 i) & iii) 10-50mg daily
Max. dose: 100-150mg daily in 2-3 divided doses
ii) 20-40mg daily
1685 Zuclopenthixol Acetate 50 mg/ml Injection N05AF05122P3001XX A* Initial treatment of acute psychoses, including mania, and exacerbations of chronic psychoses in patients not responding to available standard drugs 50-150mg IM repeated if necessary, preferably within a time interval of 2-3 days.
Additional injection may be needed 24-48 hours following the first injection
1686 Zuclopenthixol Decanoate 200 mg/ml Injection N05AF05135P2001XX B Maintenance treatment of schizophrenia and other psychoses, especially with symptoms such as hallucinations, delusions and thought disturbances along with agitation, restlessness, hostility and aggressiveness in patients not responding to available standard drugs By deep IM injection test dose 100 mg followed after 7 - 28 days by 100 - 200 mg or more followed by 200 - 400 mg at intervals of 2 - 4 weeks adjusted according to response. Maximum 600 mg weekly. Child not recommended

Halaman-halaman