Formulari Ubat KKM (FUKKM)

# Generic Name MDC Category Indications Pres. Restrictions Dosage
301 Celecoxib 200 mg Capsule M01AH01-000-C10-01-XXX A/KK i) Osteoarthritis
ii) Rheumatoid Arthritis
iii) Acute pain
iv) Ankylosing Spondylitis		 i) ADULTS: 200 mg once daily. May increase to 200 mg bid, if necessary. CHILD not recommended ii) 100mg twice daily, increased if necessary to 200 mg 2 times daily; CHILD not recommended iii) 400mg as a single dose on first day followed by 200mg once daily on subsequent days iv) Initial, 200 mg once daily or 100 mg twice daily; if no effect after 6 weeks, may increase to max. 400 mg daily in 1-2 divided doses. If no response following 2 weeks of treatment with 400 mg/day, consider discontinuation and alternative treatment
302 Celecoxib 400 mg Capsule M01AH01-000-C10-02-XXX A* i) Osteoarthritis
ii) Rheumatoid Arthritis
iii) Acute pain
iv) Ankylosing Spondylitis		 i) ADULTS: 200 mg once daily. CHILD not recommended
ii) 100 mg twice daily, increased if necessary to 200 mg 2 times daily; CHILD not recommended
iii) 400 mg as a single dose on first day followed by 200 mg once daily on subsequent days
iv) Initial, 200 mg once daily or 100 mg twice daily; if no effect after 6 weeks, may increase to max. 400 mg daily in 1-2 divided doses. If no response following 2 weeks of treatment with 400 mg/day, consider discontinuation and alternative treatment
303 Cephalexin Monohydrate 125 mg/5 ml Syrup J01DB01-010-F21-01-XXX B Respiratory tract infections, ear, nose and throat infections, urinary tract infections, obstetric and gynaecologic infections None CHILD: 25 - 100 mg/kg/day every 6 hourly. Maximum: 4 g daily
304 Cephalexin Monohydrate 250 mg Capsule J01DB01-010-C10-01-XXX B i) Respiratory tract infection, urinary tract infection
ii) Complicated, recurrent or chronic infections, bronchitis
iii) Pneumonia		 None i) 250 mg 6 hourly
ii) 250 - 500 mg 6 hourly
iii) 1 - 1.5 g 3 times daily or 4 times daily. Maximum: 6 g/day Child: 25-100 mg/kg daily in divided doses. Max: 4 g daily.
305 Cephalexin Monohydrate 250 mg Tablet J01DB01-010-T10-01-XXX B i) Respiratory tract infection, urinary tract infection
ii) Complicated, recurrent or chronic infections, bronchitis
iii) Pneumonia		 None i) 250 mg 6 hourly
ii) 250 - 500 mg 6 hourly
iii) 1 - 1.5 g 3 times daily or 4 times daily. Maximum: 6 g/day Child: 25-100 mg/kg daily in divided doses. Max: 4 g daily.
306 Cephalexin Monohydrate 250 mg/5ml Syrup J01DB01-010-F21-02-xxx B Respiratory tract infections, ear, nose and throat infections, urinary tract infections, obstetric and gynaecologic infections None CHILD: 25 - 100 mg/kg/day every 6 hourly. Maximum: 4 g daily
307 Cephalexin Monohydrate 500mg Capsule J01DB01-010-C10-02-XXX B i) Respiratory tract infection, urinary tract infection
ii) Complicated, recurrent or chronic infections, bronchitis
iii) Pneumonia		 None i) 250 mg 6 hourly
ii) 250 - 500 mg 6 hourly
iii) 1 - 1.5 g 3 times daily or 4 times daily. Maximum: 6 g/day
308 Cephalexin Monohydrate 500mg Tablet J01DB01-010-T10-02-XXX B i) Respiratory tract infection, urinary tract infection
ii) Complicated, recurrent or chronic infections, bronchitis
iii) Pneumonia		 None i) 250 mg 6 hourly
ii) 250 - 500 mg 6 hourly
iii) 1 - 1.5 g 3 times daily or 4 times daily. Maximum: 6 g/day Child: 25-100 mg/kg daily in divided doses. Max: 4 g daily.
309 Ceritinib 150mg Hard Capsules L01XE28-000-C11-01-XXX A* Monotherapy, first-line treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) None 450mg orally once daily with food until disease progression or unacceptable toxicity
310 Cetirizine HCl 10mg Tablet R06AE07-110-T10-01-XXX B Urticaria, allergic dermatoses (insect bites, atopic eczema), perennial rhinitis, allergic rhinitis ADULT and CHILD over 6 years:10 mg daily or 5 mg twice daily. Child 2-6 years: 5 mg once daily or 2.5 mg twice daily
311 Cetrimide 1-2% Lotion. D08AJ04000L6001XX C+ As shampoo and cleansing agent Apply to affected area
312 Cetrorelix 0.25mg Injection H01CC02-122-P40-01-XXX A* Prevention of premature ovulation in patients undergoing a controlled ovarian stimulation, followed by oocyte pick-up and assisted reproductive techniques None Given by SC 0.25 mg/day, given either in the morning beginning on the day 5 or 6 of ovarian stimulation or in the evening beginning on day 5, and continued until ovulation induction
313 Cetuximab 5 mg/ml Solution for Infusion L01XC06-000-P50-02-XXX A* For neo-adjuvant treatment of KRAS wild type metastatic colorectal cancer with the aim of liver resection. To be prescribed in patients with the following conditions:
i) The primary colorectal tumour has been resected or is potentially resected.
ii)The metastatic disease is confined to the liver and is unresectable
iii) Patient is fit enough to undergo surgery to resect the primary colorectal tumour and to undergo liver surgery if the metastases become resectable after treatment with cetuximab.

- The treatment is limited to 16 weeks		 Administered once a week. The very first dose is 400mg cetuximab per m2 body surface area with a recommended infusion period of 120 minutes. All subsequent weekly doses are 250mg per m2 body surface area each with a recommended infusion period of 60 minutes. The maximum infusion rate must not exceed 10mg/min.
314 Charcoal, Activated 250mg Tablet A07BA01-000-T10-01-XXX C i) Diarrhoea and food poisoning;
ii) Reduce absorption of drugs, plant, inorganic poison and chemicals in poisoning cases.		 None i) ADULT: 500mg -1000mg given 3-4 times daily.
CHILD (up to 12 years): 250-500mg 3-4 times daily.

ii) ADULT and CHILD over 12 years: initial 25-100 g or 1-2g/kg; repeat initial dose as soon as possible or 25-50 g every 4-6 hours.
CHILD (up to 12 years): 0.5 to 1 g/kg/dose (Maximum: 50 g/dose). Dose may be repeated every 2-6 hours as needed.

315 Charcoal, Activated 50 g Granules A07BA01-000-F10-01-XXX A Emergency treatment of acute oral poisoning and drug overdose None ADULT and CHILD 12 years and above:
Acute poisoning: 50 to 100g in suspension.
Severe poisoning: 50 to 100g as an initial dose followed by 20g every 4 to 6 hours.

CHILD up to 12 years: 1 g/kg/dose (Maximum: 50 g/dose).
Dose may be repeated every 4 to 6 hours as needed.

Dosing is individualised and according to product insert/protocol.
316 Chlorambucil 2mg Tablet L01AA02000T1001XX A Low grade lymphoma, chronic lymphocytic leukaemia.
Ovarian cancer		 None General : Initial :0.1 -0.2 mg/kg body weight daily for 4 - 8 weeks maintenance : given either by reduced daily dosage or intermittent course of treatment.

Chronic Lymphocytic Leukaemia: initial : 0.15mg/kg/day until total leukocyte count has fallen to 10,000peruL, then resumed treatment until 4 weeks after the end of the first course then continued at a dosage 0.1mg/kg/day.
317 Chloramphenicol 0.5% Eye Drops S01AA01-000-D20-01-XXX C Ophthalmic infections None Instill 1 drop of a 0.5% solution every 2 hr. Increase dosage interval upon improvement.
318 Chloramphenicol 1% Eye Ointment S01AA01-000-G51-01-XXX C Treatment of ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol susceptible organisms None ADULT and CHILD : Apply to the conjunctiva, a thin strip (approximately 1 cm) of ointment every 3 hours or more frequently
319 Chloramphenicol 250mg Capsule J01BA01-126-C10-01-XXX B Treatment of typhoid, paratyphoid fevers, bronchopneumonia and enteric infection None ADULT: 500 mg 4 times daily or 50 mg/kg/day in 4 divided doses. Maximum dose: 4 g/day. CHILD: 25 - 100 mg/kg/day in 4 divided doses
320 Chloramphenicol 5% w/v Ear Drops S02AA01-000-D10-01-XXX C Acute otitis media, otitis externa with perforation None Apply 2 - 3 drops into the ear 2 - 3 times daily. Not to be used for long term
321 Chloramphenicol Sodium Succinate 1 g Injection J01BA01-520-P40-01-XXX B Treatment of typhoid, paratyphoid fevers, bronchopneumonia and enteric infection None Adult:50 to 100 mg/kg/day in 4 divided doses. Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50-100 mg/kg/day in 4 divided doses
322 Chlorhexidine 1:200 (0.5%) in Alcohol (Hand Disinfectant). D08AC52-137-L99-01-XXX C+ Use as hand disinfectant for pre-surgical operation and skin disinfectant. None Pre-op surgical hand disinfection: Spread 5ml throughly over both hands and forearms, rubbing vigorously. When dry apply a further 5ml and repeat procedure. Antiseptic hand disinfection on the ward: Spread 3ml throughly over the hands and wrist rubbing vigorously until dry. Disinfection of patient's skin: Prior to surgery, apply to a sterile swab and rub thoroughly over the operation site for a minimum of 2 mins
323 Chlorhexidine Gluconate 0.2 % Mouthwash R02AA05-137-M20-01-XXX C As a gargle None Rinse mouth with 10 ml for about 1 minute twice daily
324 Chlorhexidine Gluconate 1% cream D08AC02-137-G10-01-XX C+ As a disinfectant cream. It can be used for disinfection or lubrication during gynaecological and obstetric procedures or childbirth. None Apply as required on affected area after cleaning
325 Chlorhexidine Gluconate 2% in Alcohol 70% Solution D08AC52137L9902XX C Use as disinfectant in central venous catheter care bundle Skin Preparation:
Use Chlorhexidine Gluconate 2% in Isopropyl Alcohol 70% and allow to dry.

Catheter access:
Apply to catheter ports or hubs prior to accessing the line for administering fluids or injections
326 Chlorhexidine Gluconate 4% Scrub D08AC02137M9901XX C+ Surgical hand scrub/disinfection, pre-op skin preparation Surgical hand disinfection: Apply 5ml to clean hands and forearms for 1 min. Rinse and repeat with another 5ml for a further 2 mins and then rinse and dry. General skin disinfection: Apply appropriate quantity to wet area and scrub for 1 min. Rinse thoroughly & dry
327 Chlorhexidine Gluconate 5% Solution D08AC02-137-L99-01-XXX C+ Use as antiseptic and disinfectant in:
i) Preoperative skin disinfection;
ii) Emergency disinfection of instruments;
iii) Wounds or burns.		 None To be used as diluted solution:
(i) 0.5 % w/v Aqueous solution : Dilute 10 ml of solution with 70% alcohol up to 100ml.
(ii) 0.5 % w/v Aqueous solution : Dilute 10 ml of solution with 70% alcohol up to 100ml. Immerse for 2 minutes
(iii) 0.05 % w/v aqueous solution : Dilute 1 ml of solution with 100 ml of sterile water.
328 Chlorinated Lime Powder V07AV00-000-F99-01-XXX C Antiseptic and disinfectants None Not applicable
329 Chlorinated Lime Solution & Buffered Acetate Solution D08A000-999-G99-01-XXX C Use as skin disinfectant for wound and ulcer cleansing None Apply to affected areas undiluted as a cleansing agent
330 Chloroquine Phosphate 250 mg Tablet (150mg Chloroquine base) P01BA01-162-T10-01-XXX C Treatment of malaria - acute attack None ADULT 600 mg base stat, 300 mg 6 - 8 hours later and a further 300 mg on each of 2 following days. CHILD 3 - 4 years : 150 mg base stat, 75 mg 6 hours later, then 75 mg daily for 2 days. CHILD 5 - 8 years : 300 mg stat, 150 mg 6 hours later, then 150 mg daily for 2 days

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